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Virus interference. I. The interferon

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J. Lindenmann

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Alick Isaacs

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J. Lindenmann

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Published:12 September 1957https://doi.org/10.1098/rspb.1957.0048

Abstract

During a study of the interference produced by heat-inactivated influenza virus with the growth of live virus in fragments of chick chorio-allantoic membrane it was found that following incubation of heated virus with membrane a new factor was released. This factor, recognized by its ability to induce interference in fresh pieces of chorio-allantoic membrane, was called interferon. Following a lag phase interferon was first detected in the membranes after 3 h incubation and thereafter it was released into the surrounding fluid.

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Ostler N, Britzen-Laurent N, Liebl A, Naschberger E, Lochnit G, Ostler M, Forster F, Kunzelmann P, Ince S, Supper V, Praefcke G,

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Virus interference. I. The interferon

Abstract

Footnotes