Proceedings of the Royal Society of London. Series B. Biological Sciences

    Neuromuscular junctions of rabbits immunized against acetylcholine receptors were examined with the electron microscope. Many endplates appeared normal, or showed changes which, by themselves, would not account for the blockage of neuromuscular transmission which develops after immunization. An unexpected organelle was found in the muscle fibres, associated with the endplate nuclei and the cytoplasm between them and the synaptic muscle membrane.

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