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1982Translation of exogenous messenger RNA coding for nicotinic acetylcholine receptors produces functional receptors in Xenopus oocytesProc. R. Soc. Lond. B.215241–246http://doi.org/10.1098/rspb.1982.0040

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Translation of exogenous messenger RNA coding for nicotinic acetylcholine receptors produces functional receptors in Xenopus oocytes

Eric Albert Barnard

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Ricardo Miledi

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K. Sumikawa

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Eric Albert Barnard

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Ricardo Miledi

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K. Sumikawa

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Published:22 May 1982https://doi.org/10.1098/rspb.1982.0040

Abstract

Messenger RNA extracted from the electric organ of Torpedo was injected into Xenopus oocytes. This led to the synthesis and incorporation of functional acetylcholine receptors into the membrane of the oocyte. When activated by acetylcholine these Torpedo acetylcholine receptors in the oocyte membrane opened channels whose ionic permeability resembled that of nicotinic receptors in other cells.

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This Issue

22 May 1982

Volume 215Issue 1199

Article Information

DOI:https://doi.org/10.1098/rspb.1982.0040
PubMed:6127706
Published by:Royal Society
Print ISSN:0080-4649
Online ISSN:2053-9193

History:

Manuscript received16/02/1982
Published online01/01/1997
Published in print22/05/1982

License:

Citations and impact

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