The molecular oxygen produced in photosynthesis is generated via water oxidation at a manganese–calcium cluster called the oxygen-evolving complex (OEC). While studies in biophysics, biochemistry, and structural and molecular biology are well known to provide deeper insight into the structure and workings of this system, it is often less appreciated that biomimetic modelling provides the foundation for interpreting photosynthetic reactions. The synthesis and characterization of small model complexes, which either mimic structural features of the OEC or are capable of providing insight into the mechanism of O₂ evolution, have become a vital contributor to this scientific field. Our group has contributed to these findings in recent years through synthesis of model complexes, spectroscopic characterization of these systems and probing the reactivity in the context of water oxidation. In this article we describe how models have made significant contributions ranging from understanding the structure of the water-oxidation centre (e.g. contributions to defining a tetrameric Mn₃Ca-cluster with a dangler Mn) to the ability to discriminate between different mechanistic proposals (e.g. showing that the Babcock scheme for water oxidation is unlikely).

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This Issue

Philosophical Transactions of the Royal Society B: Biological Sciences cover image

27 March 2008

Volume 363Issue 1494

Discussion Meeting Issue ‘Revealing how nature uses sunlight to split water’ organized by James Barber and Alfred Rutherford

Article Information

DOI:https://doi.org/10.1098/rstb.2007.2224
PubMed:17954438
Published by:Royal Society
Print ISSN:0962-8436
Online ISSN:1471-2970

History:

Published online17/10/2007
Published in print27/03/2008

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