Zoonotic infections are among the most common on earth and are responsible for >60 per cent of all human infectious diseases. Some of the most important and well-known human zoonoses are caused by worm or helminth parasites, including species of nematodes (trichinellosis), cestodes (cysticercosis, echinococcosis) and trematodes (schistosomiasis). However, along with social, epidemiological and environmental changes, together with improvements in our ability to diagnose helminth infections, several neglected parasite species are now fast-becoming recognized as important zoonotic diseases of humans, e.g. anasakiasis, several fish-borne trematodiasis and fasciolosis. In the present review, we discuss the current disease status of these primary helminth zoonotic infections with particular emphasis on their diagnosis and control. Advances in molecular biology, proteomics and the release of helminth genome-sequencing project data are revolutionizing parasitology research. The use of these powerful experimental approaches, and their potential benefits to helminth biology are also discussed in relation to the future control of helminth infections of animals and humans.

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This Issue

Philosophical Transactions of the Royal Society B: Biological Sciences cover image

27 September 2009

Volume 364Issue 1530

Theme Issue 'Livestock diseases and zoonoses' compiled and edited by Fiona M. Tomley and Martin W. Shirley

Article Information

DOI:https://doi.org/10.1098/rstb.2009.0089
PubMed:19687044
Published by:Royal Society
Print ISSN:0962-8436
Online ISSN:1471-2970

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Published online27/09/2009
Published in print27/09/2009

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health and disease and epidemiology